Educational Articles
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Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.
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Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury or strain caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in cats and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.
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Muscle tears are direct or indirect traumatic injuries that cause damage to muscle tissue. The most common cause is an indirect injury, or strain, caused by overstretching during athletic activities, such as running or jumping. This handout discusses muscle tears in dogs and reviews the causes of these injuries, the clinical signs, diagnostic testing, therapy, and expected prognosis.
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This handout discusses muscular dystrophy (MD), primarily in dogs. The cause of the disease is a defect in the proteins found in muscle cells. It is often an inherited disease, usually affecting young dogs. Clinical signs (usually starting as muscle weakness) and diagnosis of the condition are outlined. There is no effective treatment for the condition.
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Myasthenia gravis is a disease in which there is a malfunction in the transmission of signals between the nerves and muscles. Dogs with myasthenia gravis exhibit extreme weakness and excessive fatigue. There are two forms: inherited and acquired. Anti-acetylcholinesterase medication and immunosuppressive therapy will likely be required for the life of the dog.
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A narcoleptic episode involves sudden collapse and loss of movement in which the pet literally falls asleep, often while physically active, then wakes up abruptly and proceeds as if nothing happened. Although you may not be able to stop the episodes, you may be able to reduce the frequency and severity of events by identifying possible patterns that precipitate the incidents.
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Polyps are benign fleshy growths that originate from the cells lining a cat's nasal passages, leading to a variety of clinical signs such as sneezing, difficulty breathing, and recurrent ear infections. The various diagnostic tools and treatment approaches are explained in this handout.
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Nasopharyngeal polyps are benign idiopathic masses originating from the middle ear that extend either down the eustachian tube or into the external ear. They can cause stertor, nasal discharge, otitis, otic discharge and head tilt. Diagnosis may involve visualization through otoscopic exam or behind the soft palate, but usually needs radiographic evidence or more advanced imaging such as CT or MRI. Treatment involves debulking the mass through traction which has a high rate of recurrence, or more advanced surgery into the bulla to remove the source of the polyp.
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Nose Bleeds (Epistaxis) in cats can be extremely unsettling for the pet owner. Most acute (sudden) nosebleeds are caused by simple trauma or by upper respiratory tract infections. This handout discusses nosebleeds in cats, the various causes of this condition, first aid recommendations and possible testing to find the root cause of the problem.
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Nose Bleeds (Epistaxis) in dogs can be extremely unsettling for the pet owner. Most acute (sudden) nosebleeds are caused by simple trauma or by upper respiratory tract infections. This handout discusses nosebleeds in dogs, the various causes of this condition, first aid recommendations and possible testing to find the root cause of the problem.